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Do not use this medication if you are allergic to didanosine, or if you are also taking allopurinol (Zyloprim) or ribavirin (Rebetol, Ribasphere, Copegus Virazole). A reaction with another antigout drug, allopurinol, may cause a rash. The authors believed quinidine caused Henoch-Schonlein purpura in this patient based on a chronologic association and lack of allopurinol-associated problems following chronic therapy. Case reports have suggested that thiazide diuretics may increase the risk of allopurinol-induced hypersensitivity reactions, especially in patients with renal insufficiency. A macrophage migration-inhibition test was negative in the presence of both quinidine and allopurinol. Keep Allopurinol out of the reach of children and away from pets.
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